vPEP™ HC by D.R. Burton

The vPEP™ and vPEP™ HC are compact, hand-held OPEP (oscillatory positive expiratory pressure) devices that promote lung expansion and help to loosen and remove bronchial secretions. OPEP devices are standard of care for the clearance of patient airway secretions associated with various pulmonary ailments.

The vPEP™ devices provide a range of performance and economic benefits. The devices are intuitive, ergonomic and easy to clean. vPEP™ use is consistent with current practice and transitions easily from hospital to home.

Features & Benefits

  • Compact and ergonomic design
  • Adjustable resistance
  • Novel patented flapper
  • Hospital to home compliance
  • Easy to clean to reduce the risk of infection
  • Secretion clearance across different breath sizes


Please note that all products, services, or features of products and services may not be available in your local area. Please check with your local Vyaire representative.

Superior Expiratory Flow Bias

vPEP™ demonstrates superior expiratory flow bias compared to competitive devices. Expiratory flow bias is when peak expiratory flow (PEF) rate exceeds peak inspiratory flow (PIF) rate, generating an overall flow bias towards the mouth during exhalation. This is the fundamental principle by which secretions are evacuated from the respiratory tract and by maximizing expiratory flow bias, one can maximize the efficiency of airway clearance technologies and improve patient care.

Author & Title
Therapy Comparison
Doug Pursley, MEd, RRT-ACCS, FAARC
Effect of Inspiratory Time on PEF/PIF Ratio in Three Oscillating PEP Devices in an Adult Chronic Bronchitis Model
One of the primary factors for effective secretion clearance is the ratio of peak expiratory flow rate (PEF) to peak inspiratory flow rate (PIF). The primary purpose of this study is to examine what effect various inspiratory times have on expiratory flow bias and the PEF/PIF ratio produced by three oscillating PEP devices during simulated breathing.The secondary purpose is to evaluate any differences in flow amplitude, mean expiratory pressure, and the absolute value of peak expiratory flow between the three devices. The primary hypothesis is that as inspiratory time is prolonged, it will cause an increase in the PEF/PIF ratio and therefore improve expiratory flow bias. The secondary hypothesis is that there will be no differences in the PEF/PIF ratio, flow amplitude, mean expiratory pressure, and the absolute value of peak expiratory flow between the three devices.
The performance measures in this study — the PEF/PIF ratio, flow amplitude, and mean expiratory pressure — were chosen because collectively these measures represent the primary mechanisms of action for airway clearance devices. The importance of instructing a patient to perform a slow, prolonged inspiration during oscillating PEP therapy cannot be overstated and is integral in order to achieve the greatest possible expiratory flow bias.
Doug Pursley, MEd, RRT-ACCS, FAARC
Analysis of Three Oscillating Positive Expiratory Pressure Devices During Simulated Breathing
The primary purpose of this study is to analyze maximum expiratory flow during OPEP therapy by comparing flow-volume loops generated by the vPEP™ and competitive devices, during simulated, spontaneous breathing. Frequency, mean expiratory pressure, maximum inspiratory flow, mean pressure amplitude, and mean flow amplitude were also measured. The hypothesis for this evaluation is that the three devices will produce similar values at five different volumes.
As detailed earlier, the higher the maximum expiratory flow in relation to the maximum inspiratory flow, the greater the expiratory flow bias and presumably the greater the secretion clearance. vPEP™ demonstrated superior results across five volumes and resistance settings compared to competitive devices.

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