SUPERNO2VA™ Nasal PAP Ventilation System

Delivers positive airway pressure to stent open the upper airway, allowing for the preoperative delivery of positive pressure ventilation and oxygen for patients with a decreased level of consciousness. The SuperNO2VA™ nasal PAP ventilation device is available in medium and large sizes and is offered as a standalone mask with a head strap and as a system, kitted with a hyperinflation bag. These configurations offer flexibility as it allows the SuperNO2VA™ nasal PAP ventilation device to be used with either an anesthesia machine or with only an oxygen flow meter. 

Features & Benefits

  • Pre-oxygenate
  • Relieve upper airway obstruction due to decreased level of consciousness
  • Maintain ventilation
  • Rescue ventilate
  • Ease access for intra-oral procedures
  • Be used peri-operatively

Please note that all products, services, or features of products and services may not be available in your local area. Please check with your local Vyaire representative.


Preoperative PAP

There are several therapies used to reduce the risk of perioperative hypoxemia in adult patients. They include: CPAP/NIV, nasal PAP ventilation, nasal high flow, and other means of oxygen delivery (oxygen masks and oxygen nasal cannula). CPAP/NIV and nasal PAP devices deliver both positive pressure ventilatory support and oxygen.

Some of these therapies DELIVER OXYGEN, BUT NOT VENTILATORY SUPPORT. They include: nasal high flow oxygen therapy, and oxygen delivery via an oxygen mask or nasal cannula.

Ventilatory support may offer benefits for sedated patients at risk of hypoxemia due to upper airway obstruction. There are several studies which recommend the use of nasal CPAP (nCPAP) in particular versus oxygen delivery as it does not include a ventilatory support component.


Author & Title
Therapy Comparison
Liang et al.
Nasal Ventilation Is More Effective than Combined Oral-Nasal Ventilation during Induction of General Anesthesia in Adult Subjects
The authors hypothesized that nasal mask ventilation may be more effective than combined oral-nasal mask ventilation during induction of general anesthesia. They tested this hypothesis by comparing the volume of carbon dioxide removed per breath with nasal versus combined oral-nasal mask ventilation in nonparalyzed, apneic, adult subjects during induction of general anesthesia.
Nasal mask ventilation was more effective than combined oral-nasal mask ventilation in apneic, nonparalyzed, adult subjects during induction of general anesthesia. The authors suggest that nasal mask ventilation, rather than full facemask ventilation, be considered during induction of anesthesia.
Zeping Xu, et al.
Comparison of oxygenation and ventilation in patients undergoing colonoscopy during anesthesia using the SuperNO2VA™ nasal PAP ventilation device vs. routine care: A prospective randomized trial.
Obese patients under sedation or general anesthesia often encounter hypoxia. The aim of this study is to compare ventilation and oxygenation in obese patients under general anesthesia during colonoscopy using continuous positive airway pressure (CPAP) via a novel nasal mask (SuperNO2 VA™ nasal PAP ventilation device) vs. routine care.
SuperNO2VA at a target CPAP of 10 cmH2O increases the elapsed time to first airway intervention, and reduces the need for airway intervention, as well as the frequency and severity of hypoxia (Figure 3). Further study is needed to determine if the physiological benefit positively impacts outcome.
Francesca Dimou, et al.
Nasal positive pressure with the SuperNO2VA™ device decreases sedation-related hypoxemia during pre-bariatric surgery EGD
Pre-operative esophagogastroduodenoscopy (EGD) is becoming routine practice in patients undergoing bariatric surgery. Many patients with morbid obesity have obstructive sleep apnea (OSA), which can worsen hypoxia during an EGD. In this study, we report our outcomes using the SuperNO2VA™ device, a sealed nasal positive airway pressure mask designed to deliver high-fraction inhaled oxygen and titratable positive pressure compared to conventional nasal cannula.
This is the first study to report on the use of the SuperNO2VA™ device in bariatric patients undergoing preoperative screening EGD. The use of the SuperNO2VA™ device offers a clinical advantage compared to the current standard of care. Our data demonstrate that patients with higher BMI, higher ASA classification, and OSA were more likely to have the SuperNO2VA™ device used; yet, paradoxically, these patients were less likely to have issues with desaturation events. Use of this device can optimize care in this challenging patient population by minimizing the risks of hypoventilation.
Semhar Ghebremichael, et al.
Evaluation of SuperNO2VA™ mask technology in a clinical setting: A pilot study
The purpose of this study was to evaluate the clinical performance of the SuperNO2VA™ mask for nasal oxygenation and ventilation during pre-induction, post-induction, laryngoscopy, and tracheal intubation in adult patients requiring general anesthesia.
This observational study demonstrated that the SuperNO2VA™ mask facilitates non-invasive positive pressure ventilation while providing adequate oxygenation and ventilation during preinduction, post-induction, laryngoscopy, and tracheal intubation in elective surgical patients. Conversely, considering the novelty of this particular study, further research is warranted to determine its usefulness in patients with known/predicted difficult airways, or even during emergent situations.

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