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IOS impulse spirometry

Spirometric and airway resistance diagnostics combined in one compact device.

Tidal breathing analysis with Impulse Oscillometry (IOS) has demonstrated to be informative and differentiated in the early detection and follow up of pulmonary diseases like asthma, COPD and idiopathic pulmonary fibrosis. Therefore IOS oscillometric airway measurements complement spirometry.

  • Almost independent of patient cooperation, IOS can test a larger patient range than spirometry alone, from children, adult and geriatric patients.
  • Assessment and differentiation of airway function under quiet breathing conditions.
  • Sensitive and early detection of pulmonary obstruction. Asthma patients may be asymptomatic with normal spirometry and still show levels of increased airway resistance. IOS measures impedance at different frequencies indicative of central and peripheral airway resistance.
  • Allows differentiation of central (proximal) airways resistance and peripheral (distal) airways resistance.
  • Bronchodilator therapy often does not reach the peripheral airways. IOS can provide objective response to drug therapy even when FEV1 can't.
  • Monitor the effect of bronchial provocation on airway tone.
  • Determination of expiratory flow limitation (EFL). Abstract: Forced oscillation using impulse oscillometry provides objective responses to corticosteroids in asthmatic patients when FEV1 fails to improve. Conclusions: As forced oscillation technique is automatic and can measure multiple breaths over long periods, it is suitable for monitoring expiratory flow limitation continuously and identifying patients’ breathing close to the onset of expiratory flow limitation, where intermittent sampling may be unrepresentative. Dellacá RL, Duffy N, Pompilio PP, Aliverti A, Koulouris NG, Pedotti A, Calverley PM. E Resp J. 2007 Feb;29(2):363-74. Dipartimento di Bioingegneria, Politecnico di Milano University, Milan, Italy.
  • Automated classification and interpretation of test results.
  • IOS is available as a stand-alone device combined with spirometry measurement program (MasterScreen IOS and Vyntus IOS) or as an add-on module to the MasterScreen and Vmax Series.
Flow/Volume measurements
Type: Pneumotach
Range: 0 to ±20 L/s
Resolution: 10 mL/s
Accuracy: 0.1 to 14 L/s ±5% or 0.2 L/s (whichever is greater) or
0.2 to 12 L/s: ±2% or L/s (whichever is greater)
Resistance: < 0.05 kPa/L/s (0.5 cmH2O/L/s) at 10 L/s
CMRR: 60 dB at 50 Hz
Type: Pneumotach
Range: ± 20 L
Accuracy: 0.5 to 8 L: ± 3% or ± 0.05 L (whichever is greater)
Range: 1 mL

Mouth pressure (PM)
Type: Piezo resistive
Range: ± 2 kPa (±15 mmHg)
Accuracy: ± 2%
Resolution: 0.003 kPa (0.023 mmHg)
CMRR: 60db at 50Hz
Test signal
Type: Impulse of alternating direction
Pulse interval: 0.1 to 6 sec
Impulse length: 45 ms
Frequency range of single impulse: 0 to 100 Hz
Power spectrum: -20 dB at 40 Hz
Reference impedance: 0.2 kPa/(L/s) (2 cmH2O/(L/s))
Accuracy: < ± 2%

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